Cheapest€164.75
- Ryanair R829006:543h09:54Comiso CIYBrussels CRL
Door to door 6h 10mCO2 442.6 kgChanges 0Fixed, no changes
Comiso to Brussels flight
Flights from Comiso to Brussels start at €186.58 and take 6h 7m at their fastest.
The Flights from Comiso to Brussels starts at €186.58 and takes 6h 7m door to door, run by 1 operator over 1,799 km, with around 6 departures a day. Fares bottom out about 60 days before departure.
- 6h 7mDoor to door
- 2h 57mMoving
- €186.58From
- 442.6 kgCO2
The cheapest and the fastest on 28 September 2026
Two journeys we can sell today, with the service number each operator files them under.
Fastest€215.49
- Ryanair R277414:122h 57m17:09Comiso CIYBrussels BRU
Door to door 6h 7mCO2 442.6 kgChanges 0Fixed, no changes
Lowest CO2€196.02
- Ryanair R423507:301h 41m09:11Comiso CIYBologna BLQ
- SNCF SN330210:186h 28m16:46Bologna CentraleBruxelles Midi
Changes at Bologna, with 67 minutes between services and a walk of about 14 minutes.
Door to door 11h 13mCO2 252.6 kgChanges 1Fixed, no changes
Airlines
Speed, flexibility and what is on board. Nothing here is a rating, because we have not earned one.
| Operator | From | Fastest | Typical speed | Flexibility | On board |
|---|---|---|---|---|---|
 Ryanair | €164.75 | 5h 50m | 740 km/h | Fixed fare | Not published |
Brussels is big enough that where you sleep decides what the days look like. We sell the seat, not the room.
Where to sleep in Brussels
Sort by distance from Bruxelles Midi and you can see which places are ten minutes on foot and which are not.
Search Brussels on Booking.comOr compare on Expedia
Partner links. We do not sell accommodation. We earn a commission when a booking completes, and it never changes what you pay.
When to book Comiso to Brussels
The same search run across the whole booking window, so the shape of the curve is visible rather than described.
- €157.6790 days
- €141.7460 days
- €160.6245 days
- €160.0330 days
- €180.6821 days
- €186.5814 days
- €200.157 days
- €273.313 days
- €358.271 days
- Cheapest lead time
- Fares bottom out around 60 days ahead, at €141.74.
- How much it moves
- The gap between the cheapest and dearest lead time is 153 percent. The dearest point is €358.27, 1 days out.
- What that means
- Today sits inside the cheap window, which closes about 60 days before departure. Waiting from here has usually cost money on this corridor rather than saved it.
Which departure day costs least
Median cheapest fare for each weekday, taken across the next three weeks of real prices.
- €208.41Sun
- €193.07Mon
- €205.46Tue
- €186.58Wed
- €240.86Thu
- €223.75Fri
- €232.60Sat
Where you leave from and where you arrive
The stations, airports and ports each mode on this corridor actually uses.
Comiso
Air
- CIY
Brussels
Air
- BRU
- CRL
What the journey actually looks like
Direct or connecting, how far the route really runs, and what happens when a connection is missed.
- Direct or connecting
- 33% of the services we sell on this corridor run through without a change. The remaining 67% involve one connection.
- How far it really runs
- The route covers 1,799 km against 1,747 km in a straight line, a detour of 3 percent. Track and road geometry account for the difference.
- Where the change is
- Connections are made at Rome, Bologna, Milan, Pisa. The gap between arriving and leaving is 46 minutes, of which about 5 is walking.
- If the connection is missed
- The tightest connection we sell here has a 20 percent chance of not being made on the timetable alone. Part of this journey is a self transfer between separate tickets, so leave more time than the minimum and expect to check in again.
- First and last departure
- The first service of the day leaves Comiso at 06:54 and the last at 14:12, across 6 departures. The return direction keeps its own timetable, so the times back are not these times reversed.
Questions about Comiso to Brussels
The questions people actually ask about this journey, answered from the same prices and times the page above is built on rather than written once and left to go stale.
How long does the Flight from Comiso to Brussels take?
The Flight from Comiso to Brussels takes 6h 7m door to door, of which 2h 57m is spent moving. The route runs 1,799 km. The difference between the two times is reaching the terminal and leaving it at the far end, which every time on this page includes.
How much does the Flight from Comiso to Brussels cost?
The Flight from Comiso to Brussels starts at €186.58 for one passenger, checked on 28 September 2026. A typical fare is €191.01. Both are the total including taxes, supplier fees and our service fee, so the price here is the price at checkout.
Who runs the Flight from Comiso to Brussels?
1 operators run the Flight from Comiso to Brussels: Ryanair. Between them they file around 6 departures a day. The operator table on this page compares them on fare, journey time, cruising speed, fare conditions and what is provided on board.
Which terminal does the Flight from Comiso to Brussels use?
The Flight from Comiso to Brussels leaves from Comiso CIY and arrives at Brussels BRU. Allow about 3h 10m for reaching the departure terminal and leaving the arrival one. That time is already inside every door to door figure quoted on this page.
When should I book the Flight from Comiso to Brussels?
Fares for the Flight from Comiso to Brussels bottom out around 60 days ahead, at €141.74. The gap between the cheapest and dearest lead time across the window is 153 percent, measured on 28 September 2026. Booking inside the final week has consistently cost more.
How much CO2 does the Flight from Comiso to Brussels produce?
The Flight from Comiso to Brussels produces about 442.6 kg of CO2 per passenger over 1799 km, which works out at roughly 246 grams per passenger kilometre. That figure is for the whole journey and for one traveller, not for the vehicle.
Where these numbers come from
Observed service A carrier record shows this named operator serving this named pair, and we carry that through unchanged.
Schedules, seat counts and fares are generated by our own model until the supplier contracts are signed. Places, coordinates, operators, which operator serves which pair, and every distance are real. We would rather say that on every page than let a modelled number pass for a filed one.
Defined in full at Door to door, Fares, The booking window, Carbon
- On this page
- Every figure above was computed for Comiso to Brussels on 9 September 2026: 1799 km of route against 1747 km in a straight line, 6 services a day, 1 operators, a cheapest fare of €186.58, and 6h 7m door to door on the fastest mode. The return direction is computed separately and its numbers are not these numbers.
Related journeys
Brussels to Comiso flightCompare every mode from Comiso to BrusselsAbidjan to Brussels flightAbu Dhabi to Brussels flightAccra to Brussels flightAddis Ababa to Brussels flightAgadir to Brussels flightAjaccio to Brussels flightAl Aaroui to Brussels flightAl Hoceima to Brussels flightEl Qoseir to Brussels flightAlghero to Brussels flightAlgiers to Brussels flightAlicante to Brussels flight
BRU is not in Brussels, and the road in from it is the part of the trip nobody plans. We sell the flight and stop at the terminal door.
A car waiting when you land in Brussels
A price agreed before you fly, a driver at arrivals, and a car big enough for the bags.
Book a transfer from BRU with Welcome PickupsOr check Daytrip
Partner links. We do not operate transfers. We earn a commission on a booking, and the fare is the same as going direct.