Santiago to La Serena runs about 32 times a day, with the first departure around 06:02 and the last around 20:50. One passenger pays between €40.26 and €45.57, every fee included, depending on the operator and the way you travel. The fastest door to door is 4h 6m over 411 km, on services run by 4 operators across 1 mode.
What one seat costs
The spread between the cheapest and dearest typical fare on this corridor, across 4 operators and 1 way of making the journey. The operator sets the price on the day.
Typical fares
€40.26 to €45.57
- 122%Moves across the booking window
When it runs, leaving Santiago
No operator has filed a timetable for this direction yet, so the first and last departure below follow the pattern of the corridor. Read them as the shape of the service day rather than as times to turn up for.
- 06:02First departure
- 20:50Last departure
- 32Services per day
- 100%Run direct
Fares by date
What this journey usually costs, by departure date. It shows which days run dearer.
Typical fares
- about €77.43Mon14
- about €67.40Tue15
- about €70.35Wed16
- about €72.71Thu17
- about €66.22Fri18
- about €69.17Sat19
- about €65.63Sun20
- about €48.52Mon21
- about €45.57Tue22
- about €48.52Wed23
- about €59.14Thu24
- about €57.37Fri25
- about €57.37Sat26
- about €53.24Sun27
- about €40.26Mon28
- about €40.26Tue29
- about €42.62Wed30
- about €47.34Thu1
- about €44.39Fri2
- about €46.16Sat3
- about €44.39Sun4
Based on what this route has cost recently. The operator sets the price on the day, and the live fare is confirmed when you book.
The flight gets you into La Serena. It does not get you a bed, and neither do we.
A room in La Serena for the night the flight gets in
Sort by distance from Estación La Serena and you can see which places are ten minutes on foot and which are not.
Search La Serena on Booking.com
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When to book Santiago to La Serena
The same search run across the whole booking window, so the shape of the curve is visible rather than described.
- €46.7590 days
- €40.8560 days
- €35.5445 days
- €34.9530 days
- €44.3921 days
- €53.2414 days
- €65.637 days
- €70.353 days
- €77.431 days
- Cheapest lead time
- Fares bottom out around 30 days ahead, at €34.95.
- How much it moves
- The gap between the cheapest and most expensive lead time is 122 percent. The most expensive point is €77.43, 1 days out.
- What that means
- Today sits inside the cheap window, which closes about 30 days before departure. Waiting from here has usually cost money on this corridor rather than saved it.
Book now Fares on this route are lowest around 30 days ahead. You are inside that window.
This corridor, specifically
Facts that apply to Santiago to La Serena and to no other route on the site.
Clocks
Both ends keep the same time, so the arrival is the departure plus the journey.
The shape of it
411 km
399 km as the crow flies, 3% further by the route services actually take. The bearing runs north.
Who lives at each end
4,837,295 → 154,521
Population at the departure city and at the arrival city, which is usually what decides how often anything runs.
How we know
Observed
Every operator on this corridor is named in a carrier record.
The route
What the journey actually looks like
Direct or connecting, how far the route really runs, and what happens when a connection is missed.
- How far it really runs
- The route covers 411 km against 399 km in a straight line, a detour of 3 percent. Track and road geometry account for the difference.
The fare from LSC into La Serena is the one price on this trip we cannot show you, because it is not ours.
A car waiting when you land in La Serena
Settled in advance, so the ride into La Serena costs what it said it would rather than what the cab stand says.
Book a ride from LSC with Daytrip
Partner links. We do not operate transfers. We earn a commission on a booking, and the fare is the same as going direct.
Who runs this route
The flight gets in hours before any room is ready. Holding a bag is not what we sell.
Baggage storage near Estación La Serena
Most of the points near Estación La Serena open before the first train and close after the last one.
Check La Serena on StasherOr try Bounce
Partner links. We do not run these networks. We earn a commission on a booking, and the price is the same as going direct.
Questions about Santiago to La Serena
The questions people actually ask about this trip, answered from the same prices and times the page above is built on rather than written once and left to go stale.
How long does it take to get from Santiago to La Serena?
The fastest journey from Santiago to La Serena takes 4h 6m door to door, of which 56m is spent moving, on the flight. Most services take around 4h 8m, because that average includes slower stopping services and journeys with a connection. Times include reaching the terminal and leaving it at the far end.
How much does it cost to travel from Santiago to La Serena?
The cheapest fare from Santiago to La Serena is €40.26, as of September 13, 2026. A typical fare across the next three weeks is €63.57. Both figures are the total for one passenger, including taxes, supplier fees and our service fee, so nothing is added at checkout.
What is the cheapest way to get from Santiago to La Serena?
The cheapest way from Santiago to La Serena is by flight, at €45.57 for one passenger on September 28, 2026. That journey takes 4h 6m door to door. Cheaper is rarely faster on this corridor, and the comparison table on this page shows what each mode costs against what it saves.
When should I book Santiago to La Serena?
Fares from Santiago to La Serena bottom out around 30 days before departure, at €34.95. Across the whole booking window the gap between the cheapest and the most expensive lead time is 122 percent, measured on September 13, 2026. Booking inside the last week has consistently cost more on this corridor.
Which day of the week is cheapest for Santiago to La Serena?
Tuesday is the cheapest day to depart from Santiago to La Serena, at €45.57. That is the median of 21 priced departure days across the next three weeks, as of September 13, 2026. Shifting a departure by one day is usually worth more than shifting the booking by one week.
Which month is cheapest for Santiago to La Serena?
February is the cheapest of the next 6 months to travel from Santiago to La Serena, at €33.18 for one passenger. Each month is priced on its fifteenth, so the comparison is like for like rather than a mix of weekends and midweek departures.
Who runs service from Santiago to La Serena?
4 operators sell services from Santiago to La Serena across 1 mode: JetSMART, LAN Airlines, LAN Express, Sky Airline. Journey times, fares and fare conditions differ between them, and the operator table on this page compares all of them on speed, flexibility and what is provided on board.
Is there a direct service from Santiago to La Serena?
Every service we sell from Santiago to La Serena is direct, with around 32 departures a day and a fastest journey of 4h 6m door to door. No connection is needed, so there is no missed connection risk to plan around on this corridor.
Which station or terminal do services from Santiago to La Serena use?
Services from Santiago to La Serena by flight leave from Santiago SCL and arrive at La Serena LSC. Allow about 3h 10m in total for reaching the departure terminal and leaving the arrival one, which is already included in every door to door time on this page.
Can I change or refund a ticket from Santiago to La Serena?
0 of the 4 operators we sell from Santiago to La Serena allow a change or a refund. A change on a changeable fare costs €5.00. The operator table on this page names which is which, and the condition is shown again before you pay.
Where these numbers come from
Places, coordinates, operators, which operator serves which pair, and every distance on this page are real and come from open data. Where a corridor has a filed timetable the departure times are real too, and ferry fares are the prices the operators publish themselves.
Observed service A carrier record shows this named operator serving this named pair, and we carry that through unchanged.
Where no operator publishes a fare for a corridor, the price here is our own estimate, worked out from the real distance and the real operator through a fare curve that follows lead time, day of the week and season. It tells you roughly what the journey costs. It is not a seat anyone has agreed to sell, and the payment step will not take it.
Defined in full at Door to door, Fares, The booking window, Carbon, Distances
- On this page
- Every figure above was computed for Santiago to La Serena on September 13, 2026: 411 km of route against 399 km in a straight line, 32 services a day, 4 operators a cheapest fare of €40.26, and 4h 6m door to door on the fastest mode. The return direction is computed separately and its numbers are not these numbers.
The flight is the simple part. What you do once you are in La Serena is somebody else's catalog.
Day trips out of La Serena and across Chile
Day trips that leave La Serena in the morning and cover a good part of Chile by evening.
See La Serena on CivitatisOr browse GetYourGuide
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The two ends, compared
Santiago reaches 69 places in 19 countries on services we hold, over distances from 59 to 11,648 km. La Serena reaches 7 places in 1 countries, from 296 to 1,275 km.
Other ways to make this journey
Leaving Santiago
- 69Places you can leave for
- 19Countries
- 34Operators
Arriving in La Serena
Leaving La Serena
- 7Places you can leave for
- 1Countries
- 4Operators