Cheapest€24.93
- FlixBus FB349706:316h 43m13:14MühldreieckPraha Florenc
Door to door 7h 27mCO2 13.6 kgChanges 0Changeable for a fee
Mainz to Prague bus
Buses from Mainz to Prague start at €31.53 and take 7h 27m at their fastest.
The Buses from Mainz to Prague starts at €31.53 and takes 7h 27m door to door, run by 1 operator over 504 km, with around 2 departures a day. Fares bottom out about 60 days before departure.
- 7h 27mDoor to door
- 6h 43mMoving
- €31.53From
- 13.6 kgCO2
The cheapest and the fastest on September 30, 2026
Two journeys we can sell today, with the service number each operator files them under.
Bus operators
Speed, flexibility and what is on board. Nothing here is a rating, because we have not earned one.
| Operator | From | Fastest | Typical speed | Flexibility | On board |
|---|---|---|---|---|---|
 FlixBus | €24.93 | 7h 19m | 72 km/h | Changeable | Power outlets, Restrooms, Wi-Fi |
The bus gets you into Prague. It does not get you a bed, and neither do we.
Rooms within reach of Praha hlavni nadrazi
Sort by distance from Praha hlavni nadrazi and you can see which places are ten minutes on foot and which are not.
Search Prague on Booking.comOr compare on Expedia
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When to book Mainz to Prague
The same search run across the whole booking window, so the shape of the curve is visible rather than described.
- €29.3390 days
- €21.6360 days
- €27.1345 days
- €23.2830 days
- €24.9321 days
- €35.9314 days
- €37.037 days
- €52.983 days
- €88.181 days
- Cheapest lead time
- Fares bottom out around 60 days ahead, at €21.63.
- How much it moves
- The gap between the cheapest and most expensive lead time is 308 percent. The most expensive point is €88.18, 1 days out.
- What that means
- Today sits inside the cheap window, which closes about 60 days before departure. Waiting from here has usually cost money on this corridor rather than saved it.
Which departure day costs least
Median cheapest fare for each weekday, taken across the next three weeks of real prices.
- €37.03Sun
- €32.63Mon
- €31.53Tue
- €35.93Wed
- €50.23Thu
- €45.28Fri
- €37.58Sat
Where you leave from and where you arrive
The stations, airports and ports each mode on this corridor actually uses.
Mainz
Bus
- Mühldreieck
- Pariser Tor
Prague
Bus
- Praha Florenc
- Nádraží Modřany
What the journey actually looks like
Direct or connecting, how far the route really runs, and what happens when a connection is missed.
- Direct or connecting
- 20% of the services we sell on this corridor run through without a change. The remaining 80% involve one connection.
- How far it really runs
- The route covers 504 km against 439 km in a straight line, a detour of 15 percent. Track and road geometry account for the difference.
- Where the change is
- Connections are made at Heidelberg, Pilsen, Chemnitz, Nuremberg. The gap between arriving and leaving is 46 minutes, of which about 5 is walking.
- If the connection is missed
- The tightest connection we sell here has a 20 percent chance of not being made on the timetable alone. Part of this journey is a self transfer between separate tickets, so leave more time than the minimum and expect to check in again.
- First and last departure
- The first service of the day leaves Mainz at 06:31 and the last at 07:30, across 2 departures. The return direction keeps its own timetable, so the times back are not these times reversed.
Questions about Mainz to Prague
The questions people actually ask about this trip, answered from the same prices and times the page above is built on rather than written once and left to go stale.
How long does the Coach from Mainz to Prague take?
The Coach from Mainz to Prague takes 7h 27m door to door, of which 6h 43m is spent moving. The route runs 504 km. The difference between the two times is reaching the terminal and leaving it at the far end, which every time on this page includes.
How much does the Coach from Mainz to Prague cost?
The Coach from Mainz to Prague starts at €31.53 for one passenger, checked on September 30, 2026. A typical fare is €32.63. Both are the total including taxes, supplier fees and our service fee, so the price here is the price at checkout.
Who runs the Coach from Mainz to Prague?
1 operators run the Coach from Mainz to Prague: FlixBus. Between them they file around 2 departures a day. The operator table on this page compares them on fare, journey time, cruising speed, fare conditions and what is provided on board.
Which terminal does the Coach from Mainz to Prague use?
The Coach from Mainz to Prague leaves from Mühldreieck and arrives at Praha Florenc. Allow about 44m for reaching the departure terminal and leaving the arrival one. That time is already inside every door to door figure quoted on this page.
When should I book the Coach from Mainz to Prague?
Fares for the Coach from Mainz to Prague bottom out around 60 days ahead, at €21.63. The gap between the cheapest and most expensive lead time across the window is 308 percent, measured on September 30, 2026. Booking inside the final week has consistently cost more.
How much CO2 does the Coach from Mainz to Prague produce?
The Coach from Mainz to Prague produces about 13.6 kg of CO2 per passenger over 504 km, which works out at roughly 27 grams per passenger kilometer. That figure is for the whole journey and for one traveler, not for the vehicle.
What is provided on board the Coach from Mainz to Prague?
Operators on the Coach from Mainz to Prague publish Power outlets, Restrooms, Wi-Fi. That is what 1 carriers on this corridor state about their own fleets, across a journey of 7h 27m door to door. Where a carrier publishes nothing, this page lists nothing for it.
Where these numbers come from
Derived from service area No carrier record names this exact pair. The operators listed publish a service area covering both places at a distance their mode plausibly carries people, which is evidence that the corridor is served and not evidence of a specific service. Pages state which, because presenting the two as the same thing would be dishonest.
Schedules, seat counts and fares are generated by our own model until the supplier contracts are signed. Places, coordinates, operators, which operator serves which pair, and every distance are real. We would rather say that on every page than let a modeled number pass for a filed one.
Defined in full at Door to door, Fares, The booking window, Carbon
- On this page
- Every figure above was computed for Mainz to Prague on September 9, 2026: 504 km of route against 439 km in a straight line, 2 services a day, 1 operators, a cheapest fare of €31.53, and 7h 27m door to door on the fastest mode. The return direction is computed separately and its numbers are not these numbers.
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The bus is the simple part. What you do once you are in Prague is somebody else's catalog.
What to book in Prague before you go
The tickets worth having in advance, because the line at the door is usually the whole morning.
See Prague on GetYourGuideOr browse Viator
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