Milan to Prague bus

Buses from Milan to Prague start at €33.73 and take 9h 10m at their fastest.

MilanMilanPraguePrague
The Golden Portal use to be the main entrance to the cathedral. Bohemian royals entered through this portal on coronation day. The colorful mosaic above the portal was created in the fourteenth century by Venetian artisans and depicts The Last Judgment. St. Vitus Cathedral, dominates the skyline wherever you are in city. The cathedral was commissioned by Charles IV, and construction began in 1344. it took almost six centuries to complete, with the final phase of construction in the period 1873-1929. It is the largest and most important church in Prague, St. Vitus Cathedral has also been the site of the coronation of Czech kings and queens. The Great South Tower of the Cathedral was founded in the late 14th century, then reconstructed in the 16th and again in the 18th centuries. The tower holds the biggest bell in the Czech Republic, called Žikmund, which dates from the 16th century.

The Buses from Milan to Prague starts at €33.73 and takes 9h 10m door to door, run by 2 operators over 646 km, with around 24 departures a day. Fares bottom out about 60 days before departure.

Checked September 9, 2026Priced for September 29, 2026One passenger, all fees included

  • 9h 10mDoor to door
  • 8h 26mMoving
  • €33.73From
  • 17.4 kgCO2
Real services

The cheapest and the fastest on September 29, 2026

Two journeys we can sell today, with the service number each operator files them under.

Cheapest€28.78
  1. FlixBus FB603408:408h 32m17:12Milano LampugnanoPraha Florenc

Door to door 9h 16mCO2 17.4 kgChanges 0Changeable for a fee

Carriers

Bus operators

Speed, flexibility and what is on board. Nothing here is a rating, because we have not earned one.

Every operator we sell on this corridor. Speed is the carrier's own typical cruising speed, not the average over this route.
OperatorFromFastest
FlixBus€28.789h 9m
Flixbus CEE South€29.339h 10m

The bus gets you into Prague. It does not get you a bed, and neither do we.

A hotel room

Rooms within reach of Praha hlavni nadrazi

Sort by distance from Praha hlavni nadrazi and you can see which places are ten minutes on foot and which are not.

Partner links. We do not sell accommodation. We earn a commission when a booking completes, and it never changes what you pay.

Booking window

When to book Milan to Prague

The same search run across the whole booking window, so the shape of the curve is visible rather than described.

  1. €27.6890 days
  2. €25.4860 days
  3. €29.8845 days
  4. €28.2330 days
  5. €30.4321 days
  6. €37.5814 days
  7. €43.637 days
  8. €62.883 days
  9. €76.631 days
Cheapest lead time
Fares bottom out around 60 days ahead, at €25.48.
How much it moves
The gap between the cheapest and most expensive lead time is 201 percent. The most expensive point is €76.63, 1 days out.
What that means
Today sits inside the cheap window, which closes about 60 days before departure. Waiting from here has usually cost money on this corridor rather than saved it.
Day of the week

Which departure day costs least

Median cheapest fare for each weekday, taken across the next three weeks of real prices.

  1. €39.23Sun
  2. €34.28Mon
  3. €33.73Tue
  4. €37.58Wed
  5. €44.18Thu
  6. €41.43Fri
  7. €41.98Sat
Terminals

Where you leave from and where you arrive

The stations, airports and ports each mode on this corridor actually uses.

Milan

Bus
  • Milano Lampugnano
  • Orioshuttle - Milano Stazione Centrale

Prague

Bus
  • Praha Florenc
  • Nádraží Modřany
The journey

What the journey actually looks like

Direct or connecting, how far the route really runs, and what happens when a connection is missed.

How far it really runs
The route covers 646 km against 646 km in a straight line, a detour of 2 percent. Track and road geometry account for the difference.
First and last departure
The first service of the day leaves Milan at 06:21 and the last at 21:29, across 24 departures. The return direction keeps its own timetable, so the times back are not these times reversed.
The alternatives

Buses against the other ways to make this journey

The same corridor, door to door, with every mode that runs it.

Door to door means the whole journey, including reaching the terminal and leaving it at the far end. Fares are the cheapest sold on each mode.
ModeDoor to doorMovingAt the endsFromCO2Per day
Flight4h 25m1h 15m3h 10m€69.17163.6 kg48
Coach9h 10m8h 26m44m€33.7317.4 kg24

Questions about Milan to Prague

The questions people actually ask about this trip, answered from the same prices and times the page above is built on rather than written once and left to go stale.

How long does the Coach from Milan to Prague take?

The Coach from Milan to Prague takes 9h 10m door to door, of which 8h 26m is spent moving. The route runs 646 km. The difference between the two times is reaching the terminal and leaving it at the far end, which every time on this page includes.

How much does the Coach from Milan to Prague cost?

The Coach from Milan to Prague starts at €33.73 for one passenger, checked on September 29, 2026. A typical fare is €33.18. Both are the total including taxes, supplier fees and our service fee, so the price here is the price at checkout.

Who runs the Coach from Milan to Prague?

2 operators run the Coach from Milan to Prague: FlixBus, Flixbus CEE South. Between them they file around 24 departures a day. The operator table on this page compares them on fare, journey time, cruising speed, fare conditions and what is provided on board.

Which terminal does the Coach from Milan to Prague use?

The Coach from Milan to Prague leaves from Milano Lampugnano and arrives at Praha Florenc. Allow about 44m for reaching the departure terminal and leaving the arrival one. That time is already inside every door to door figure quoted on this page.

Is the Coach the best way from Milan to Prague?

Traveling from Milan to Prague by Flight costs €69.17 and takes 4h 25m door to door, against 9h 10m by Coach. Which is better depends on whether the money or the hours matter more on this trip. The comparison table on this page shows every mode side by side.

When should I book the Coach from Milan to Prague?

Fares for the Coach from Milan to Prague bottom out around 60 days ahead, at €25.48. The gap between the cheapest and most expensive lead time across the window is 201 percent, measured on September 29, 2026. Booking inside the final week has consistently cost more.

How much CO2 does the Coach from Milan to Prague produce?

The Coach from Milan to Prague produces about 17.4 kg of CO2 per passenger over 646 km, which works out at roughly 27 grams per passenger kilometer. That figure is for the whole journey and for one traveler, not for the vehicle.

What is provided on board the Coach from Milan to Prague?

Operators on the Coach from Milan to Prague publish Power outlets, Restrooms, Wi-Fi. That is what 2 carriers on this corridor state about their own fleets, across a journey of 9h 10m door to door. Where a carrier publishes nothing, this page lists nothing for it.

Where these numbers come from

Observed service A carrier record shows this named operator serving this named pair, and we carry that through unchanged.

Schedules, seat counts and fares are generated by our own model until the supplier contracts are signed. Places, coordinates, operators, which operator serves which pair, and every distance are real. We would rather say that on every page than let a modeled number pass for a filed one.

Defined in full at Door to door, Fares, The booking window, Carbon

On this page
Every figure above was computed for Milan to Prague on September 9, 2026: 646 km of route against 646 km in a straight line, 24 services a day, 2 operators, a cheapest fare of €33.73, and 9h 10m door to door on the fastest mode. The return direction is computed separately and its numbers are not these numbers.

Related journeys

The bus is the simple part. What you do once you are in Prague is somebody else's catalog.

A guided tour group

What to book in Prague before you go

The tickets worth having in advance, because the line at the door is usually the whole morning.

Partner links. We do not sell tours or tickets. We earn a commission on a booking, and it never changes the price.

Plan with Ori

Ori, the trip planner

Ask it something like this

Milan to Prague bus · Orlero