Cheapest€65.63
- United Airlines UA352518:111h 23m19:34Knoxville TYSChicago ORD
Door to door 4h 33mCO2 185.0 kgChanges 0Fixed, no changes
Knoxville to Chicago flight
Flights from Knoxville to Chicago start at €76.84 and take 4h 32m at their fastest.
The Flights from Knoxville to Chicago starts at €76.84 and takes 4h 32m door to door, run by 5 operators over 752 km, with around 40 departures a day. Fares bottom out about 30 days before departure.
- 4h 32mDoor to door
- 1h 22mMoving
- €76.84From
- 185.0 kgCO2
The cheapest and the fastest on September 29, 2026
Two journeys we can sell today, with the service number each operator files them under.
Fastest€67.99
- American Airlines AA629006:181h 22m07:40Knoxville TYSChicago MDW
Door to door 4h 32mCO2 185.0 kgChanges 0Fixed, no changes
Airlines
Speed, flexibility and what is on board. Nothing here is a rating, because we have not earned one.
| Operator | From | Fastest |
|---|---|---|
 American Airlines | €66.81 | 4h 31m |
 GoJet Airlines | €67.40 | 4h 32m |
 SkyWest | €66.81 | 4h 31m |
| United Airlines | €65.63 | 4h 31m |
 Air Wisconsin | €68.58 | 4h 32m |
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When to book Knoxville to Chicago
The same search run across the whole booking window, so the shape of the curve is visible rather than described.
- €79.2090 days
- €65.6360 days
- €57.3745 days
- €54.4230 days
- €70.3521 days
- €76.8414 days
- €92.187 days
- €99.263 days
- €115.781 days
- Cheapest lead time
- Fares bottom out around 30 days ahead, at €54.42.
- How much it moves
- The gap between the cheapest and most expensive lead time is 113 percent. The most expensive point is €115.78, 1 days out.
- What that means
- Today sits inside the cheap window, which closes about 30 days before departure. Waiting from here has usually cost money on this corridor rather than saved it.
Which departure day costs least
Median cheapest fare for each weekday, taken across the next three weeks of real prices.
- €76.84Sun
- €78.02Mon
- €77.43Tue
- €81.56Wed
- €100.44Thu
- €94.54Fri
- €95.72Sat
Where you leave from and where you arrive
The stations, airports and ports each mode on this corridor actually uses.
Knoxville
Air
- TYS
Chicago
Air
- ORD
- MDW
What the journey actually looks like
Direct or connecting, how far the route really runs, and what happens when a connection is missed.
- How far it really runs
- The route covers 752 km against 730 km in a straight line, a detour of 3 percent. Track and road geometry account for the difference.
- First and last departure
- The first service of the day leaves Knoxville at 06:11 and the last at 20:53, across 40 departures. The return direction keeps its own timetable, so the times back are not these times reversed.
Questions about Knoxville to Chicago
The questions people actually ask about this trip, answered from the same prices and times the page above is built on rather than written once and left to go stale.
How long does the Flight from Knoxville to Chicago take?
The Flight from Knoxville to Chicago takes 4h 32m door to door, of which 1h 22m is spent moving. The route runs 752 km. The difference between the two times is reaching the terminal and leaving it at the far end, which every time on this page includes.
How much does the Flight from Knoxville to Chicago cost?
The Flight from Knoxville to Chicago starts at €76.84 for one passenger, checked on September 13, 2026. A typical fare is €81.56. Both are the total including taxes, supplier fees and our service fee, so the price here is the price at checkout.
Who runs the Flight from Knoxville to Chicago?
5 operators run the Flight from Knoxville to Chicago: American Airlines, GoJet Airlines, SkyWest, United Airlines, Air Wisconsin. Between them they file around 40 departures a day. The operator table on this page compares them on fare, journey time, cruising speed, fare conditions and what is provided on board.
Which terminal does the Flight from Knoxville to Chicago use?
The Flight from Knoxville to Chicago leaves from Knoxville TYS and arrives at Chicago MDW. Allow about 3h 10m for reaching the departure terminal and leaving the arrival one. That time is already inside every door to door figure quoted on this page.
When should I book the Flight from Knoxville to Chicago?
Fares for the Flight from Knoxville to Chicago bottom out around 30 days ahead, at €54.42. The gap between the cheapest and most expensive lead time across the window is 113 percent, measured on September 13, 2026. Booking inside the final week has consistently cost more.
How much CO2 does the Flight from Knoxville to Chicago produce?
The Flight from Knoxville to Chicago produces about 185.0 kg of CO2 per passenger over 752 km, which works out at roughly 246 grams per passenger kilometer. That figure is for the whole journey and for one traveler, not for the vehicle.
Where these numbers come from
Observed service A carrier record shows this named operator serving this named pair, and we carry that through unchanged.
Schedules, seat counts and fares are generated by our own model until the supplier contracts are signed. Places, coordinates, operators, which operator serves which pair, and every distance are real. We would rather say that on every page than let a modeled number pass for a filed one.
Defined in full at Door to door, Fares, The booking window, Carbon
- On this page
- Every figure above was computed for Knoxville to Chicago on September 13, 2026: 752 km of route against 730 km in a straight line, 40 services a day, 5 operators, a cheapest fare of €76.84, and 4h 32m door to door on the fastest mode. The return direction is computed separately and its numbers are not these numbers.
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